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NDB ID: 5MHJ    PDB ID: 5MHJ 


Title:

ICP4 DNA-BINDING DOMAIN, LACKING INTRINSICALLY DISORDERED REGION, IN COMPLEX WITH 12MER DNA DUPLEX FROM ITS OWN PROMOTER

Molecular Description:

Major viral transcription factor ICP4/DNA Complex

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Tunnicliffe, R.B., Lockhart-Cairns, M.P., Levy, C., Mould, A.P., Jowitt, T.A., Sito, H., Baldock, C., Sandri-Goldin, R.M., Golovanov, A.P.
The herpes viral transcription factor ICP4 forms a novel DNA recognition complex. 
Nucleic Acids Res., , pp. - , 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 127.254   b = 39.084   c = 90.443 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX (1.11.1_2575: ???) program. The R value is 0.1988 for 25167 reflections in the resolution range 45.22 to 2.117 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)