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NDB ID: 5NNU    PDB ID: 5NNU 


Title:

KSHV URACIL-DNA GLYCOSYLASE, PRODUCT COMPLEX WITH DSDNA EXHIBITING DUPLEX NUCLEOTIDE FLIPPING

Molecular Description:

Uracil-DNA glycosylase/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Earl, C., Bagneris, C., Zeman, K., Cole, A., Barrett, T., Savva, R.
A structurally conserved motif in gamma-herpesvirus uracil-DNA glycosylases elicits duplex nucleotide-flipping. 
Nucleic Acids Res., 46, pp. 4286 - 4300, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 82.1   b = 70.8   c = 140.25 (Ångstroms)

α = 90.0   β = 94.36   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2451 for 32502 reflections in the resolution range 49.2 to 2.97 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)