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NDB ID: 5OC6    PDB ID: 5OC6 


Title:

CRYSTAL STRUCTURE OF HUMAN TRNA-DIHYDROURIDINE(20) SYNTHASE DSRBD IN COMPLEX WITH A 22 NUCLEOTIDE DSRNA

Molecular Description:

tRNA-dihydrouridine(20) synthase [NAD(P)+]-like/RNA Complex

Deposited:

2017-06-29

Released:

2018-12-26

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Bou-Nader, C., Barraud, P., Pecqueur, L., Perez, J., Velours, C., Shepard, W., Fontecave, M., Tisne, C., Hamdane, D.
Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2. 
Nucleic Acids Res., 47, pp. 3117 - 3126, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 58.44   b = 115.56   c = 66.62 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the BUSTER program. The R value is 0.228 for 3855 reflections in the resolution range 43.65 to 3.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)