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NDB ID: 5OPH    PDB ID: 5OPH 


Title:

G-QUADRUPLEX STRUCTURE OF DNA OLIGONUCLEOTIDE CONTAINING GGGGCC REPEATS LINKED TO ALS AND FTD

Molecular Description:

DNA (5'-D(*GP*GP*GP*GP*CP*CP*GP*GP*GP*GP*CP*CP*GP*GP*GP*GP*CP*CP*GP*GP*(BGM)P*G)-3')

Structural Keywords:

QUADRUPLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Brcic, J., Plavec, J.
NMR structure of a G-quadruplex formed by four d(G4C2) repeats: insights into structural polymorphism. 
Nucleic Acids Res., , pp. - , 2018.

Experimental Information:

SOLUTION NMR

Cell Constants:

a =   b =   c = (Ångstroms)

α =   β =   γ = (degrees)

Number of Models:

Number of Models: 10 Structures

Sample Details:

1.0 mM DNA (5'-D(*GP*GP*GP*GP*CP*CP*GP*GP*GP*GP*CP*CP*GP*GP*GP*GP*CP*CP*GP*GP*(BGM)P*G)-3'), 30 mM potassium chloride, 20 mM potassium phosphate, 90% H2O/10% D2O 90% H2O/10% D2O