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NDB ID: 5T00    PDB ID: 5T00 


Title:

HUMAN CTCF ZNF3-7 AND METHYLATED DNA COMPLEX

Molecular Description:

Transcriptional repressor CTCF/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hashimoto, H., Wang, D., Horton, J.R., Zhang, X., Corces, V.G., Cheng, X.
Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. 
Mol. Cell, 66, pp. 711 - 720.e3, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 40.99   b = 44.91   c = 86.8 (Ångstroms)

α = 98.33   β = 92.4   γ = 94.8 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2196 for 30975 reflections in the resolution range 41.956 to 2.19 Ångstroms with Fobs >  2.01 sigma(Fobs) and with I >  0.0 sigma(I)