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NDB ID: 5T01    PDB ID: 5T01 


Title:

HUMAN C-JUN DNA BINDING DOMAIN HOMODIMER IN COMPLEX WITH METHYLATED DNA

Molecular Description:

Transcription factor AP-1/DNA Complex

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hong, S., Wang, D., Horton, J.R., Zhang, X., Speck, S.H., Blumenthal, R.M., Cheng, X.
Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta. 
Nucleic Acids Res., 45, pp. 2503 - 2515, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 158.871   b = 42.49   c = 45.167 (Ångstroms)

α = 90.0   β = 98.01   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1949 for 23712 reflections in the resolution range 27.75 to 1.89 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)