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NDB ID: 5TPY    PDB ID: 5TPY     NAKB(beta): 5TPY 


Title:

CRYSTAL STRUCTURE OF AN EXONUCLEASE RESISTANT RNA FROM ZIKA VIRUS

Molecular Description:

RNA (71-MER)

Deposited:

2016-10-21

Released:

2016-12-14

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Akiyama, B.M., Laurence, H.M., Massey, A.R., Costantino, D.A., Xie, X., Yang, Y., Shi, P.Y., Nix, J.C., Beckham, J.D., Kieft, J.S.
Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease. 
Science, 354, pp. 1148 - 1152, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 64 2 2

Cell Constants:

a = 111.679   b = 111.679   c = 90.826 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1933 for 15501 reflections in the resolution range 55.839 to 2.805 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)