A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 19-Jul-2017 number of released structures: 9000
Search for released structures

NDB ID: 5TWR    PDB ID: 5TWR 


Title:

PRE-CATALYTIC TERNARY COMPLEX OF HUMAN POLYMERASE MU (H329A) MUTANT WITH INCOMING NONHYDROLYZABLE UMPNPP

Molecular Description:

DNA-directed DNA/RNA polymerase mu/DNA Complex

Structural Keywords:

B DOUBLE HELIX, NICKED

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Moon, A.F., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.
Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme Polymerase Mu 
Nucleic Acids Res., , pp. - , 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 59.703   b = 68.606   c = 109.767 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine: 1.9_1692) program. The R value is 0.1644 for 36150 reflections in the resolution range 28.708 to 1.9 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)