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NDB ID: 5UEG    PDB ID: 5UEG 


Title:

RNA PRIMER-TEMPLATE COMPLEX WITH GUANOSINE DINUCLEOTIDE G(5')PPPP(5')G LIGAND

Molecular Description:

RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3')

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Zhang, W., Tam, C.P., Walton, T., Fahrenbach, A.C., Birrane, G., Szostak, J.W.
Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex. 
Proc. Natl. Acad. Sci. U.S.A., 114, pp. 7659 - 7664, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 3

Cell Constants:

a = 48.416   b = 48.416   c = 81.965 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.21197 for 6081 reflections in the resolution range 50.0 to 2.6 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)