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NDB ID: 5V3F    PDB ID: 5V3F 


Title:

CO-CRYSTAL STRUCTURE OF THE FLUOROGENIC RNA MANGO

Molecular Description:

RNA (31-MER)

Structural Keywords:

A DOUBLE HELIX, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Trachman, R.J., Demeshkina, N.A., Lau, M.W.L., Panchapakesan, S.S.S., Jeng, S.C.Y., Unrau, P.J., Ferre-D'Amare, A.R.
Structural basis for high-affinity fluorophore binding and activation by RNA Mango. 
Nat. Chem. Biol., 13, pp. 807 - 813, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 63.199   b = 63.199   c = 138.413 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1965 for 29469 reflections in the resolution range 46.668 to 1.7 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)