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NDB ID: 5VBS    PDB ID: 5VBS 


Title:

STRUCTURAL BASIS FOR A SIX LETTER ALPHABET INCLUDING GATCKX

Molecular Description:

Moloney murine leukemia virus reverse transcriptase catalytic fragment/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Singh, I., Kim, M.J., Molt, R.W., Hoshika, S., Benner, S.A., Georgiadis, M.M.
Structure and Biophysics for a Six Letter DNA Alphabet that Includes Imidazo[1,2-a]-1,3,5-triazine-2(8H)-4(3H)-dione (X) and 2,4-Diaminopyrimidine (K). 
ACS Synth Biol, 6, pp. 2118 - 2129, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 54.999   b = 145.643   c = 46.876 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.21 for 38305 reflections in the resolution range 33.722 to 1.749 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)