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NDB ID: 5VH7    PDB ID: 5VH7 


Title:

STRUCTURE AND DYNAMICS OF RNA REPEAT EXPANSIONS THAT CAUSE HUNTINGTON'S DISEASE AND MYOTONIC DYSTROPHY TYPE 1

Molecular Description:

RNA (5'-R(*GP*AP*CP*CP*AP*GP*CP*AP*G)-3')

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Chen, J.L., VanEtten, D.M., Fountain, M.A., Yildirim, I., Disney, M.D.
Structure and dynamics of RNA repeat expansions that cause Huntington's Disease and myotonic dystrophy type 1. 
Biochemistry, , pp. - , 2017.

Experimental Information:

SOLUTION NMR

Cell Constants:

a =   b =   c = (Ångstroms)

α =   β =   γ = (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 20 Structures

Sample Details:

0.5 mM NA Adenosine, Cytidine,Guanosine, Uridine RNA (5'-R(*GP*AP*CP*CP*AP*GP*CP*AP*G)-3'), 5.0 mM potassium phosphate, 0.25 mM EDTA, 100% D2O 100% D2O