A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 17-Oct-2018 number of released structures: 9817
Search for released structures

NDB ID: 5VHE    PDB ID: 5VHE 


Title:

DHX36 IN COMPLEX WITH THE C-MYC G-QUADRUPLEX

Molecular Description:

DEAH (Asp-Glu-Ala-His) box polypeptide 36/DNA Complex

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Chen, M.C., Tippana, R., Demeshkina, N.A., Murat, P., Balasubramanian, S., Myong, S., Ferre-D'Amare, A.R.
Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. 
Nature, 558, pp. 465 - 469, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 72.526   b = 79.282   c = 212.077 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2427 for 12607 reflections in the resolution range 39.641 to 3.793 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)