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NDB ID: 5VS0    PDB ID: 5VS0 


Title:

HUMAN DNA POLYMERASE BETA 8-OXOG:DC EXTENSION WITH DTTP AFTER 80 S

Molecular Description:

human DNA polymerase beta/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Reed, A.J., Suo, Z.
Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. 
J. Am. Chem. Soc., 139, pp. 9684 - 9690, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 50.6   b = 80.3   c = 55.4 (Ångstroms)

α = 90.0   β = 107.6   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2048 for 23241 reflections in the resolution range 52.81 to 2.1 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)