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NDB ID: 5VYC    PDB ID: 5VYC 

Title:

CRYSTAL STRUCTURE OF THE HUMAN 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH DENR-MCT-1.

Molecular Description:

40S ribosomal protein S19
40S ribosomal protein S20
40S ribosomal protein S21
40S ribosomal protein S23
40S ribosomal protein S26
40S ribosomal protein S28
40S ribosomal protein S29
Ribosomal protein S27a
Receptor of activated protein C kinase 1
40S ribosomal protein S2
40S ribosomal protein S6
40S ribosomal protein S9
40S ribosomal protein S12
40S ribosomal protein S13
40S ribosomal protein S14
40S ribosomal protein S15a
40S ribosomal protein S24
40S ribosomal protein S25
40S ribosomal protein S27
40S ribosomal protein S30
40S ribosomal protein SA
40S ribosomal protein S3a
40S ribosomal protein S3
40S ribosomal protein S4
X isoform
40S ribosomal protein S5
40S ribosomal protein S7
40S ribosomal protein S8
40S ribosomal protein S10
40S ribosomal protein S11
40S ribosomal protein S15
40S ribosomal protein S16
40S ribosomal protein S17
40S ribosomal protein S18
60S ribosomal protein L41
Malignant T-cell-amplified sequence 1
Density-regulated protein/RNA Complex

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 36 protein sequences

Primary Citation:

Lomakin, I.B., Stolboushkina, E.A., Vaidya, A.T., Zhao, C., Garber, M.B., Dmitriev, S.E., Steitz, T.A.
Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1. 
Cell Rep, 20, pp. 521 - 528, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 334.67   b = 597.13   c = 336.5 (Ångstroms)

α = 90.0   β = 120.29   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.3227 for 281673 reflections in the resolution range 116.931 to 6.0 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)

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