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NDB ID: 5VZJ    PDB ID: 5VZJ 


Title:

STRUCTURE OF A TWELVE COMPONENT MPP6-NUCLEAR RNA EXOSOME COMPLEX BOUND TO RNA

Molecular Description:

Exosome complex component RRP45
SKI6
RRP43
RRP46
RRP42
MTR3
RRP40
RRP4
CSL4
RRP6
DIS3
M-phase phosphoprotein 6 homolog/RNA Complex

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 12 protein sequences

Primary Citation:

Wasmuth, E.V., Zinder, J.C., Zattas, D., Das, M., Lima, C.D.
Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase. 
Elife, 6, pp. - , 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 141.09   b = 213.592   c = 225.909 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2192 for 100411 reflections in the resolution range 44.247 to 3.3 Ångstroms with Fobs >  1.39 sigma(Fobs) and with I >  0.0 sigma(I)