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NDB ID: 5W1C    PDB ID: 5W1C 


Title:

CRYSTAL STRUCTURE OF MBP FUSED ACTIVATION-INDUCED CYTIDINE DEAMINASE (AID) IN COMPLEX WITH CYTIDINE

Molecular Description:

MBP fused activation-induced cytidine deaminase
Activation-induced cytidine deaminase/DNA Complex

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Qiao, Q., Wang, L., Meng, F.L., Hwang, J.K., Alt, F.W., Wu, H.
AID Recognizes Structured DNA for Class Switch Recombination. 
Mol. Cell, 67, pp. 361 - 373.e4, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 2 1

Cell Constants:

a = 125.456   b = 39.824   c = 155.304 (Ångstroms)

α = 90.0   β = 90.27   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2341 for 26403 reflections in the resolution range 125.455 to 3.18 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)