A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 22-Nov-2017 number of released structures: 9218
Search for released structures

NDB ID: 5W4K    PDB ID: 5W4K 


Title:

CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH KLEBSAZOLICIN AND BOUND TO MRNA AND A-, P- AND E-SITE TRNAS AT 2.7A RESOLUTION

Molecular Description:

RIBOSOME

Structural Keywords:

Nucleic Acid Sequence:

Click to show/hide 8 nucleic acid sequences

Protein Sequence:

Click to show/hide 50 protein sequences

Primary Citation:

Metelev, M., Osterman, I.A., Ghilarov, D., Khabibullina, N.F., Yakimov, A., Shabalin, K., Utkina, I., Travin, D.Y., Komarova, E.S., Serebryakova, M., Artamonova, T., Khodorkovskii, M., Konevega, A.L., Sergiev, P.V., Severinov, K., Polikanov, Y.S.
Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel. 
Nat. Chem. Biol., 13, pp. 1129 - 1136, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 209.64   b = 449.06   c = 622.01 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2091 for 1572843 reflections in the resolution range 155.503 to 2.7 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)