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NDB ID: 5W5H    PDB ID: 5W5H 


Title:

HUMAN IFIT1 DIMER WITH M7GPPP-AAAA

Molecular Description:

Interferon-induced protein with tetratricopeptide repeats 1/RNA Complex

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Abbas, Y.M., Martinez-Montero, S., Cencic, R., Pelletier, J., Damha, M.J., Pawelek, P.D., Nagar, B.
Structural insights into IFIT1 dimerization and conformational changes associated with mRNA binding 
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 4

Cell Constants:

a = 184.355   b = 184.355   c = 88.762 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.22 for 32445 reflections in the resolution range 42.01 to 2.79 Ångstroms with Fobs >  2.79 sigma(Fobs) and with I >  0.0 sigma(I)