A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 12-Dec-2018 number of released structures: 9940
Search for released structures

NDB ID: 5W6Q    PDB ID: 5W6Q 


Title:

STRUCTURAL BASIS FOR RECOGNITION OF ARTIFICIAL DNA BY AN EVOLVED KLENTAQ VARIANT

Molecular Description:

Moloney murine leukemia virus reverse transcriptase catalytic fragment/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Singh, I., Laos, R., Hoshika, S., Benner, S.A., Georgiadis, M.M.
Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide. 
Nucleic Acids Res., 46, pp. 7977 - 7988, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 199.282   b = 114.611   c = 90.516 (Ångstroms)

α = 90.0   β = 91.88   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2131 for 57623 reflections in the resolution range 49.132 to 2.66 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)