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NDB ID: 5WN3    PDB ID: 5WN3 


Title:

APE1 F266A EXONUCLEASE SUBSTRATE COMPLEX WITH A C/T MISMATCH

Molecular Description:

DNA-(apurinic or apyrimidinic site) lyase/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Whitaker, A.M., Flynn, T.S., Freudenthal, B.D.
Molecular snapshots of APE1 proofreading mismatches and removing DNA damage. 
Nat Commun, 9, pp. 399 - 399, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 71.144   b = 65.545   c = 91.441 (Ångstroms)

α = 90.0   β = 110.08   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.211 for 53376 reflections in the resolution range 24.76 to 2.0 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)