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NDB ID: 5WO0    PDB ID: 5WO0 


Title:

DNA POLYMERASE BETA SUBSTRATE COMPLEX WITH INCOMING 5-FODUTP

Molecular Description:

DNA polymerase beta/DNA Complex

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Schaich, M.A., Smith, M.R., Cloud, A.S., Holloran, S.M., Freudenthal, B.D.
Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues. 
Chem. Res. Toxicol., , pp. - , 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 50.728   b = 79.637   c = 55.289 (Ångstroms)

α = 90.0   β = 107.28   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2012 for 55295 reflections in the resolution range 31.79 to 1.6 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)