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NDB ID: 5XBL    PDB ID: 5XBL 


Title:

STRUCTURE OF NUCLEASE IN COMPLEX WITH ASSOCIATED PROTEIN

Molecular Description:

CRISPR-associated endonuclease Cas9/Csn1
Associated protein/RNA Complex

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Guo, M., Wang, S., Zhu, Y., Wang, S., Xiong, Z., Yang, J., Xu, Z., Huang, Z.
Structural basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR protein 
Nature, 546, pp. 436 - 439, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 108.406   b = 69.756   c = 129.24 (Ångstroms)

α = 90.0   β = 105.73   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2399 for 45371 reflections in the resolution range 41.78 to 3.052 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)