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NDB ID: 5XN0    PDB ID: 5XN0 


Title:

HIV-1 REVERSE TRANSCRIPTASE Q151M:DNA BINARY COMPLEX

Molecular Description:

Pol protein/DNA Complex

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Yasutake, Y., Hattori, S.I., Hayashi, H., Matsuda, K., Tamura, N., Kohgo, S., Maeda, K., Mitsuya, H.
HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir. 
Sci Rep, 8, pp. 1624 - 1624, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

H 3

Cell Constants:

a = 284.091   b = 284.091   c = 95.605 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1868 for 88833 reflections in the resolution range 48.605 to 2.596 Ångstroms with Fobs >  1.98 sigma(Fobs) and with I >  0.0 sigma(I)