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NDB ID: 5XUS    PDB ID: 5XUS 


Title:

CRYSTAL STRUCTURE OF LACHNOSPIRACEAE BACTERIUM ND2006 CPF1 IN COMPLEX WITH CRRNA AND TARGET DNA (TTTA PAM)

Molecular Description:

CRISPR-associated endonuclease Cpf1/RNA/DNA Complex

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Yamano, T., Zetsche, B., Ishitani, R., Zhang, F., Nishimasu, H., Nureki, O.
Structural basis for the canonical and non-canonical PAM recognition by CRISPR-Cpf1 
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 103.205   b = 103.205   c = 363.909 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1807 for 69046 reflections in the resolution range 49.64 to 2.5 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)