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NDB ID: 5XZ1    PDB ID: 5XZ1 


Title:

CRYSTAL STRUCTURE OF THE HOMO SAPIENS CYTOPLASMIC RIBOSOMAL DECODING SITE IN COMPLEX WITH G418

Molecular Description:

RNA (5'-R(*UP*GP*CP*GP*UP*CP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3')

Structural Keywords:

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Kanazawa, H., Tsurumi, N., Baasov, T., Kondo, J.
Structural studies of aminoglycoside antibiotics G418 and its derivatives with readthrough activities
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 47.399   b = 32.528   c = 96.484 (Ångstroms)

α = 90.0   β = 95.58   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.0 for 5949 reflections in the resolution range 48.013 to 3.008 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)