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NDB ID: 5YTD    PDB ID: 5YTD 


Title:

LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN A CLOSED TERNARY COMPLEX WITH THE NATURAL BASE PAIR 5FC:DGTP

Molecular Description:

DNA polymerase I
thermostable/DNA Complex

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Yi, C., Zeng, H., Mondal, M., Song, R., Zhang, J., Xia, B., Liu, M., Zhu, C., He, B., Gao, Y.Q.
Unnatural cytosine bases recognized as thymines by DNA polymerases via the formation of the Watson-Crick geometry. 
Angew. Chem. Int. Ed. Engl., , pp. - , 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 2 1

Cell Constants:

a = 108.909   b = 108.909   c = 90.539 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.19822 for 40252 reflections in the resolution range 94.32 to 2.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)