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NDB ID: 5YWT    PDB ID: 5YWT 


Title:

CRYSTAL STRUCTURE OF TREX1 IN COMPLEX WITH A DUPLEX DNA WITH 3' OVERHANG

Molecular Description:

Three-prime repair exonuclease 1/DNA Complex

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Huang, K.W., Liu, T.C., Liang, R.Y., Chu, L.Y., Cheng, H.L., Chu, J.W., Hsiao, Y.Y.
Structural basis for overhang excision and terminal unwinding of DNA duplexes by TREX1 
PLoS Biol., 16, pp. e2005653 - e2005653, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 66.17   b = 80.35   c = 85.22 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.196 for 49630 reflections in the resolution range 28.79 to 1.7 Ångstroms with Fobs >  0.34 sigma(Fobs) and with I >  0.0 sigma(I)