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NDB ID: 5Z23    PDB ID: 5Z23 


Title:

CRYSTAL STRUCTURE OF THE NUCLEOSOME CONTAINING A CHIMERIC HISTONE H3/CENP-A CATD

Molecular Description:

Histone H3.1
Histone H3-like centromeric protein A
Histone H3.1
Histone H4
Histone H2A type 1-B/E
Histone H2B type 1-J/DNA Complex

Deposited:

2017-12-28

Released:

2019-02-13

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Arimura, Y., Tachiwana, H., Takagi, H., Hori, T., Kimura, H., Fukagawa, T., Kurumizaka, H.
The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism. 
Nat Commun, 10, pp. 576 - 576, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 99.641   b = 100.745   c = 173.431 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2055 for 45284 reflections in the resolution range 47.884 to 2.73 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)