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NDB ID: 5Z2T    PDB ID: 5Z2T 


Title:

CRYSTAL STRUCTURE OF DNA-BOUND DUX4-HD2

Molecular Description:

Double homeobox protein 4/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Dong, X., Zhang, W., Wu, H., Huang, J., Zhang, M., Wang, P., Zhang, H., Chen, Z., Chen, S.J., Meng, G.
Structural basis of DUX4/IGH-driven transactivation. 
Leukemia, 32, pp. 1466 - 1476, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 51.61   b = 51.61   c = 166.55 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2779 for 7266 reflections in the resolution range 49.297 to 2.623 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)