A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 12-Dec-2018 number of released structures: 9940
Search for released structures

NDB ID: 5Z3N    PDB ID: 5Z3N 


Title:

STRUCTURE OF LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS HOST-GUEST COMPLEX WITH THE UNNATURAL BASE 5FC PAIR WITH DA

Molecular Description:

DNA polymerase I
thermostable/DNA Complex

Structural Keywords:

RH TRIPLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Yi, C., Zeng, H., Mondal, M., Song, R., Zhang, J., Xia, B., Liu, M., Zhu, C., He, B., Gao, Y.Q.
Unnatural cytosine bases recognized as thymines by DNA polymerases via the formation of the Watson-Crick geometry. 
Angew. Chem. Int. Ed. Engl., , pp. - , 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 2 1

Cell Constants:

a = 107.947   b = 107.947   c = 90.121 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.18568 for 42010 reflections in the resolution range 93.48 to 1.91 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)