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NDB ID: 5ZFZ    PDB ID: 5ZFZ 


Title:

CRYSTAL STRUCTURE OF HUMAN DUX4 HOMEODOMAINS BOUND TO A12T DNA MUTANT

Molecular Description:

Double homeobox protein 4/DNA Complex

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Li, Y., Wu, B., Liu, H., Gao, Y., Yang, C., Chen, X., Zhang, J., Chen, Y., Gu, Y., Li, J., Ma, J., Gan, J.
Structural basis for multiple gene regulation by human DUX4. 
Biochem. Biophys. Res. Commun., 505, pp. 1161 - 1167, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 32 2 1

Cell Constants:

a = 65.013   b = 65.013   c = 151.661 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1876 for 26645 reflections in the resolution range 29.877 to 1.9 Ångstroms with Fobs >  1.51 sigma(Fobs) and with I >  0.0 sigma(I)