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NDB ID: 5ZKJ    PDB ID: 5ZKJ 


Title:

HUMAN EXOG-H140A IN COMPLEX WITH RNA/DNA HYBRID DUPLEX

Molecular Description:

Nuclease EXOG
mitochondrial
RNA
DNA Complex

Deposited:

2018-03-24

Released:

2019-04-03

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Wu, C.C., Lin, J.L.J., Yang-Yen, H.F., Yuan, H.S.
A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication. 
Nucleic Acids Res., 47, pp. 5405 - 5419, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

H 3

Cell Constants:

a = 167.576   b = 167.576   c = 105.438 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1831 for 25986 reflections in the resolution range 28.434 to 2.798 Ångstroms with Fobs >  1.98 sigma(Fobs) and with I >  0.0 sigma(I)