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NDB ID: 5ZKO    PDB ID: 5ZKO 


Title:

CRYSTAL STRUCTURE OF THE CRTC2-CREB-CRE COMPLEX

Molecular Description:

Cyclic AMP-responsive element-binding protein 1
CREB-regulated transcription coactivator 2/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Song, Y., Zhai, L., Valencia Swain, J., Chen, Y., Wang, P., Chen, L., Liu, Y., Xiang, S.
Structural Insights into the CRTC2-CREB Complex Assembly on CRE. 
J. Mol. Biol., 430, pp. 1926 - 1939, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 50.3   b = 41.32   c = 122.58 (Ångstroms)

α = 90.0   β = 90.61   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2443 for 9336 reflections in the resolution range 46.707 to 3.05 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)