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NDB ID: 5ZOF    PDB ID: 5ZOF 


Title:

CRYSTAL STRUCTURE OF D181A/R192F HFEN1 IN COMPLEX WITH DNA

Molecular Description:

Flap endonuclease 1/DNA Complex

Deposited:

2018-04-13

Released:

2019-01-30

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Xu, H., Shi, R., Han, W., Cheng, J., Xu, X., Cheng, K., Wang, L., Tian, B., Zheng, L., Shen, B., Hua, Y., Zhao, Y.
Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1. 
Nucleic Acids Res., 46, pp. 11315 - 11325, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 47.67   b = 92.73   c = 102.78 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.237 for 22086 reflections in the resolution range 27.82 to 2.249 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)