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NDB ID: 5C52    PDB ID: 5C52 


Title:

PROBING THE STRUCTURAL AND MOLECULAR BASIS OF NUCLEOTIDE SELECTIVITY BY HUMAN MITOCHONDRIAL DNA POLYMERASE GAMMA

Molecular Description:

DNA polymerase subunit gamma-1
DNA polymerase subunit gamma-2
mitochondrial/DNA Complex

Deposited:

2015-06-19

Released:

2016-05-11

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Sohl, C.D., Szymanski, M.R., Mislak, A.C., Shumate, C.K., Amiralaei, S., Schinazi, R.F., Anderson, K.S., Yin, Y.W.
Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma. 
Proc.Natl.Acad.Sci.USA, 112, pp. 8596 - 8601, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 217.277   b = 217.277   c = 165.865 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.3112 for 44279 reflections in the resolution range 51.213 to 3.637 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)