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NDB ID: 5E5A    PDB ID: 5E5A 


Title:

CRYSTAL STRUCTURE OF THE CHROMATIN-TETHERING DOMAIN OF HUMAN CYTOMEGALOVIRUS IE1 PROTEIN BOUND TO THE NUCLEOSOME CORE PARTICLE

Molecular Description:

Histone H3.2
Histone H4
Histone H2A
Histone H2B 1.1
C-terminal domain of Regulatory protein IE1/DNA Complex

Deposited:

2015-10-08

Released:

2016-02-03

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 5 protein sequences

Primary Citation:

Fang, Q., Chen, P., Wang, M., Fang, J., Yang, N., Li, G., Xu, R.M.
Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome 
Elife, 5, pp. - , 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 106.7   b = 109.474   c = 181.976 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1978 for 52359 reflections in the resolution range 30.0 to 2.809 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)