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NDB ID: 5KG2    PDB ID: 5KG2 


Title:

HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: REACTION FIRST WITH 1 MM MN2+ FOR 1800S THEN WITH 5 MM MN2+ FOR 60S AT 37 DEGREE

Molecular Description:

DNA polymerase eta/DNA Complex

Deposited:

2016-06-12

Released:

2016-06-22

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Gao, Y., Yang, W.
Capture of a third Mg2+ is essential for catalyzing DNA synthesis. 
Science, 352, pp. 1334 - 1337, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 98.27   b = 98.27   c = 82.19 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1854 for 55216 reflections in the resolution range 19.707 to 1.6 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)