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NDB ID: 6A8R    PDB ID: 6A8R 


Title:

CRYSTAL STRUCTURE OF DUX4 HD2 DOMAIN ASSOCIATED WITH ERG DNA BINDING SITE

Molecular Description:

Double homeobox protein 4/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Dong, X., Zhang, H., Cheng, N., Li, K., Meng, G.
DUX4HD2-DNAERGstructure reveals new insight into DUX4-Responsive-Element 
Leukemia, , pp. - , 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31

Cell Constants:

a = 32.55   b = 32.55   c = 126.591 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2008 for 19612 reflections in the resolution range 28.189 to 1.6 Ångstroms with Fobs >  1.96 sigma(Fobs) and with I >  0.0 sigma(I)