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NDB ID: 6B0B    PDB ID: 6B0B 


Title:

CRYSTAL STRUCTURE OF HUMAN APOBEC3H

Molecular Description:

APOBEC3H
MCherry/RNA Complex

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Shaban, N.M., Shi, K., Lauer, K.V., Carpenter, M.A., Richards, C.M., Salamango, D., Wang, J., Lopresti, M.W., Banerjee, S., Levin-Klein, R., Brown, W.L., Aihara, H., Harris, R.S.
The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism. 
Mol. Cell, 69, pp. 75 - 86.e9, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 1 2

Cell Constants:

a = 101.293   b = 101.293   c = 211.217 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.353354 for 18872 reflections in the resolution range 49.2504 to 3.28006 Ångstroms with Fobs >  1.32616 sigma(Fobs) and with I >  0.0 sigma(I)