NDB ID: 6B0R    PDB ID: 6B0R     NAKB(beta): 6B0R 

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Title:

ZINC FINGER DOMAIN OF WT1(-KTS FORM) WITH M342R MUTATION AND 14+1MER OLIGONUCLEOTIDE WITH 3' TRIPLET TGG

Molecular Description:

Wilms tumor protein/DNA Complex

Deposited:

2017-09-14

Released:

2018-01-03

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Wang, D., Horton, J.R., Zheng, Y., Blumenthal, R.M., Zhang, X., Cheng, X.
Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites. 
Nucleic Acids Res., 46, pp. 3864 - 3877, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 153.94   b = 35.113   c = 87.148 (Ångstroms)

α = 90.0   β = 110.03   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2092 for 39284 reflections in the resolution range 31.321 to 1.818 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)

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Biological Assembly coordinates (pdb format) 1 2 

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

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XML | Coordinates only (xml format, GNU compressed(.gz))

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