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NDB ID: 6BTF    PDB ID: 6BTF 


Title:

DNA POLYMERASE BETA I260Q TERNARY COMPLEX

Molecular Description:

DNA polymerase beta/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Liptak, C., Mahmoud, M.M., Eckenroth, B.E., Moreno, M.V., East, K., Alnajjar, K.S., Huang, J., Towle-Weicksel, J.B., Doublie, S., Loria, J.P., Sweasy, J.B.
I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity. 
Nucleic Acids Res., , pp. - , 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 50.61   b = 79.879   c = 55.382 (Ångstroms)

α = 90.0   β = 107.4   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1788 for 82376 reflections in the resolution range 37.551 to 1.75 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)