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NDB ID: 6BZ1    PDB ID: 6BZ1 


Title:

MEF2 CHIMERA D83V MUTANT/DNA COMPLEX

Molecular Description:

Myocyte-specific enhancer factor 2B/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Lei, X., Kou, Y., Fu, Y., Rajashekar, N., Shi, H., Wu, F., Xu, J., Luo, Y., Chen, L.
The Cancer Mutation D83V Induces an alpha-Helix to beta-Strand Conformation Switch in MEF2B. 
J. Mol. Biol., 430, pp. 1157 - 1172, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 32

Cell Constants:

a = 78.44   b = 78.44   c = 111.041 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.14091 for 14964 reflections in the resolution range 42.99 to 2.97 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)