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NDB ID: 6C1Y    PDB ID: 6C1Y 


Title:

MBD OF HUMAN MECP2 IN COMPLEX WITH METHYLATED DNA

Molecular Description:

Methyl-CpG-binding protein 2/DNA Complex

Deposited:

2018-01-05

Released:

2018-02-14

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Lei, M., Tempel, W., Chen, S., Liu, K., Min, J.
Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. 
Biochim Biophys Acta Gene Regul Mech, 1862, pp. 194409 - 194409, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 40.753   b = 47.359   c = 54.623 (Ångstroms)

α = 68.15   β = 89.83   γ = 65.98 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2334 for 13799 reflections in the resolution range 39.85 to 2.3 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)