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NDB ID: 6CCW    PDB ID: 6CCW 


Title:

HYBRID-2 FORM HUMAN TELOMERIC G QUADRUPLEX IN COMPLEX WITH EPIBERBERINE

Molecular Description:

DNA (26-MER)

Deposited:

2018-02-07

Released:

2018-06-20

Structural Keywords:

QUADRUPLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Lin, C., Wu, G., Wang, K., Onel, B., Sakai, S., Shao, Y., Yang, D.
Molecular Recognition of the Hybrid-2 Human Telomeric G-Quadruplex by Epiberberine: Insights into Conversion of Telomeric G-Quadruplex Structures. 
Angew. Chem. Int. Ed. Engl., 57, pp. 10888 - 10893, 2018.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 15 Structures

Sample Details:

880 uM DNA (26-MER), 880 uM epiberberine, 90% H2O/10% D2O 90% H2O/10% D2O