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NDB ID: 6CF2    PDB ID: 6CF2 


Title:

CRYSTAL STRUCTURE OF HIV-1 REV (RESIDUES 1-93)-RNA APTAMER COMPLEX

Molecular Description:

HIV-1 Rev-RNA aptamer complex

Structural Keywords:

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

Dearborn, A.D., Eren, E., Watts, N.R., Palmer, I.W., Kaufman, J.D., Steven, A.C., Wingfield, P.T.
Structure of an RNA Aptamer that Can Inhibit HIV-1 by Blocking Rev-Cognate RNA (RRE) Binding and Rev-Rev Association. 
Structure, 26, pp. 1187 - , 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 1 2 1

Cell Constants:

a = 64.19   b = 97.68   c = 87.836 (Ångstroms)

α = 90.0   β = 109.7   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.0 for 9172 reflections in the resolution range 38.0 to 3.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)