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NDB ID: 6CQI    PDB ID: 6CQI 


Title:

2.42A CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TOPOISOMERASE I IN COMPLEX WITH AN OLIGONUCLEOTIDE MTS2-11

Molecular Description:

DNA topoisomerase 1/DNA Complex

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Cao, N., Thirunavukkarasu, A., Tan, K., Tse-Dinh, Y.-C.
2.42A Crystal structure of Mycobacterium tuberculosis Topoisomerase I in complex with an oligonucleotide MTS2-11 
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 68.777   b = 44.977   c = 129.229 (Ångstroms)

α = 90.0   β = 90.6   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2259 for 29706 reflections in the resolution range 47.0 to 2.42 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)