NDB ID: 6CTU    PDB ID: 6CTU 

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Title:

TERNARY COMPLEX CRYSTAL STRUCTURE OF DNA POLYMERASE BETA WITH A DIDEOXY TERMINATED PRIMER WITH CFCL, BETA, GAMMA DCTP ANALOGUE

Molecular Description:

DNA polymerase beta/DNA Complex

Deposited:

2018-03-23

Released:

2018-06-20

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Batra, V.K., Oertell, K., Beard, W.A., Kashemirov, B.A., McKenna, C.E., Goodman, M.F., Wilson, S.H.
Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. 
Biochemistry, 57, pp. 3934 - 3944, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 50.81   b = 79.636   c = 55.483 (Ångstroms)

α = 90.0   β = 107.78   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1735 for 31138 reflections in the resolution range 23.72 to 1.9 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)

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Biological Assembly coordinates (pdb format) 1

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

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