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NDB ID: 6D12    PDB ID: 6D12 


Title:

CRYSTAL STRUCTURE OF C-TERMINAL XRRM DOMAIN OF HUMAN LARP7 BOUND TO 7SK STEM-LOOP 4 RNA

Molecular Description:

La-related protein 7/RNA Complex

Structural Keywords:

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Eichhorn, C.D., Yang, Y., Repeta, L., Feigon, J.
Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7. 
Proc. Natl. Acad. Sci. U.S.A., 115, pp. E6457 - E6466, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 47.91   b = 34.03   c = 95.01 (Ångstroms)

α = 90.0   β = 95.18   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2299 for 14297 reflections in the resolution range 94.622 to 2.205 Ångstroms with Fobs >  1.37 sigma(Fobs) and with I >  0.0 sigma(I)