NDB ID: 6D2U    PDB ID: 6D2U     NAKB(beta): 6D2U 

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Title:

SOLUTION STRUCTURE OF A ULTRA-HIGH AFFINITY MACROCYCLE BOUND TO HIV-1 TAR RNA

Molecular Description:

DAB-VAL-ARG-THR-ARG-LYS-GLY-ARG-ARG-ILE-NOR-ILE-DPR-PRO/RNA Complex

Deposited:

2018-04-13

Released:

2018-12-12

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Shortridge, M.D., Wille, P.T., Jones, A.N., Davidson, A., Bogdanovic, J., Arts, E., Karn, J., Robinson, J.A., Varani, G.
An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb. 
Nucleic Acids Res., 47, pp. 1523 - 1531, 2019.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 10 Structures

Sample Details:

1.7 mM DAB-VAL-ARG-THR-ARG-LYS-GLY-ARG-ARG-ILE-NOR-ILE-DPR-PRO, 1.2 mM RNA (29-MER), 0.01 mM EDTA, 20 mM potassium phosphate, 10 mM sodium chloride, 95% H2O/5% D2O 95% H2O/5% D2O

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